Publications

Ancestry-specific polygenic risk scores improve clinical assessments of breast cancer risk in diverse populations
George Busby, Scott Kulm, Alessandro Bolli, Jen Kintzle, Paolo Di Domenico, John Neary, Daniel Morganstern, Giordano Bottà
Preprint 2024

European Society of Human Genetics Poster Presentations
Glasgow, Scotland, United Kingdom, June 10-13, 2023

P16.003.C Low-coverage genotyping-by-sequencing with accurate long HiFi reads and optimized imputation
Michael Eberle, George Busby, Jen Kintzle, Paolo Di Domenico, Gregory Conception, Geoff Henno, Giordano Bottà

P18.062.B Analyses of Polygenic Risk Scores that Consider Individual-Level Admixture Proportions Outperform Single Ancestry Approaches
Scott Kulm, Jen Kintzle, Alessandro Bolli, Paolo Di Domenico, Giordano Bottà, George Busby

P19.032.D Recalibrating polygenic risk scores to country-specific incidence
Jen Kintzle, Scott Kulm, Alessandro Bolli, Paolo Di Domenico, Giordano Bottà, George Busby

Ancestry-specific polygenic risk scores are risk enhancers for clinical cardiovascular disease assessments
George Busby, Scott Kulm, Alessandro Bolli, Jen Kintzle, Paolo Di Domenico, Giordano Bottà
Nature Communications Nov 2023

Cost-effectiveness analysis of implementing polygenic risk score in a workplace cardiovascular disease prevention program
Deo Mujwara, Jen Kintzle, Paolo Di Domenico, George Busby, Giordano Bottà
Frontiers in Public Health July 2023

Integrating polygenic risk scores into clinical breast cancer models: Influence on prediction in diverse cohorts
George Busby, Alessandro Bolli, Jen Kintzle, Scott Kulm, John Neary, Paolo Di Domenico, Daniel Morgeanstern, Giordano Bottà
Journal of Clinical Oncology May 2023